Brand names include:Gabapin / Gabin
Active ingredient: gabapentin.
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Neurontin is a modern highly effective drug for the peroral monotherapy of the neuropathic pain. Its active component is gabapentin.
This drug provides the anticonvulsive and antiepileptic action. It carries out the function of the breaking mediator in the central nervous system. It easily penetrates into the tissue of the brain and prevents spasms caused by the maximal electric shock, chemical drugs includi ng inhibitors of synthesis of GABA, and also conditioned by the genetic factors.
After the consumption of the drug the maximal concentration in the body is observed in 2-3 hours. The consumption of meals does not provide a weakening of the efficiency, and therefore the tablets of Neurontin may be taken both before and after meals. The active components are excreted by kidneys from the body in the invariable type in 7-8 hours after the use.
Neurontin helps to get rid of the different partial spasms and also neuropathic pain. This remedy differs from its analogs by a wide range of the advantages and useful properties. The maximal effect of the action is gained in several hours after the use when the concentration of Gabapentin in plasma allows it to effectively act to the source of the pain and convulsions.
The final mechanism of the pharmacological action is not indicated because this drug provides the action as to the receptors and chemicals which cause the disease symptoms in each clinical case depending on the level of the affection of the central nervous system.
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Directions for the use:
- treatment of the neuropathic pain in adults at the age of 18 years and older
- partial convulsions
- neuropathy in patients older than 18 years old
- Depending on the type of the disease (epilepsy or neuropathy) patients are prescribed certain dosage regimen and recommendations for the use
- For epilepsy and neuropathy it is prescribed the same initial dosage with further adjustment
- Adults and children older than 12 years old are prescribed 300 mg 3 times per day in the first day, the following increase of the daily dose up to the most effective and safe one.
- During the treatment the dose may ne increased and reduced depending on the tolerance of the drug and clinical image of the disease.
- Children at the age from 3 to 12 years old are prescribed the initial dosage of 25-35 mg/kg per day. The daily dosage should be divided into 3 uses.
- Neurontin is contraindicated for the treatment of the neuropathic pain and spasms in children younger than 3 years old and also in case of pancreatitis and generalized epileptic seizures.
- In case of the pancreatic diabetes and sharp renal failure it is needed to take the drug in the lowered doses.
- It is recommended to take the drug with special caution during pregnancy and also renal failure.
- In the period of the lactation it is reasonable to use the bottle-feeding of a child.
Possible Side effects
In case of the correct use of Neurontin in the recommended dosage the side effects appear rarely (less than 2% of cases) and they are caused by the individual intolerance of the active components of the drug.
The commons side reactions are pain in the stomach, sryness in the mouth, and disorder of the sleep regimen. If the allergic reactions appear, it is necessary to reduce the daily dose of the drug or see your doctor for a piece of advice.